Mountain child: systematic literature review.

Objectives This systematic review identifies and reviews both peer-reviewed and 'grey' literature, across a range of disciplines and from diverse sources, relating to the condition of children living in mountain communities in low- and middle-income countries. Findings The literature on poverty in these communities does not generally focus on the particular vulnerabilities of children or the impact of intersecting vulnerabilities on the most marginalised members of communities. However, this literature does contribute analyses of the broader context and variety of factors impacting on human development in mountainous areas. The literature on other areas of children's lives - health, nutrition, child mortality, education, and child labour - focuses more specifically on children's particular vulnerabilities or experiences. However, it sometimes lacks the broader analysis of the many interrelated characteristics of a mountainous environment which impact on children's situations. Themes Nevertheless, certain themes recur across many disciplines and types of literature, and point to some general conclusions: mountain poverty is influenced by the very local specificities of the physical environment; mountain communities are often politically and economically marginalised, particularly for the most vulnerable within these communities, including children; and mountain communities themselves are an important locus for challenging and interrupting cycles of increasing inequality and disadvantage. While this broad-scale review represents a modest first step, its findings provide the basis for further investigation

An Introduction to the Integrated Community-Engaged Learning and Ethical Reflection Framework (I-CELER)

Cultivating ethical Science, Technology, Engineering, and Mathematics researchers and practitioners requires movement beyond reducing ethical instruction to the rational exploration of moral quandaries via case studies and into the complexity of the ethical issues that students will encounter within their careers. We designed the Integrated Community-Engaged Learning and Ethical Reflection (I-CELER) framework as a means to promote the ethical becoming of future STEM practitioners. This paper provides a synthesis of and rationale for I-CELER for promoting ethical becoming based on scholarly literature from various social science fields, including social anthropology, moral development, and psychology. This paper proceeds in five parts. First, we introduce the state of the art of engineering ethics instruction; argue for the need of a lens that we describe as ethical becoming; and then detail the Specific Aims of the I-CELER approach. Second, we outline the three interrelated components of the project intervention. Third, we detail our convergent mixed methods research design, including its qualitative and quantitative counterparts. Fourth, we provide a brief description of what a course modified to the I-CELER approach might look like. Finally, we close by detailing the potential impact of this study in light of existing ethics education research within STEM

Rapid Viscoelastic Deformation Slows Marine Ice Sheet Instability at Pine Island Glacier

The ice sheets of the Amundsen Sea Embayment (ASE) are vulnerable to the marine ice sheet instability (MISI), which could cause irreversible collapse and raise sea levels by over a meter. The uncertain timing and scale of this collapse depend on the complex interaction between ice, ocean, and bedrock dynamics. The mantle beneath the ASE is likely less viscous (∼1018 Pa s) than the Earth’s average mantle (∼1021 Pa s). Here we show that an effective equilibrium between Pine Island Glacier’s retreat and the response of a weak viscoelastic mantle can reduce ice mass lost by almost 30% over 150 years. Other components of solid Earth response—purely elastic deformations and geoid perturbations—provide less stability than the viscoelastic response alone. Uncertainties in mantle rheology, topography, and basal melt affect how much stability we expect, if any. Our study indicates the importance of considering viscoelastic uplift during the rapid retreat associated with MISI.Plain Language SummaryPortions of the West Antarctic Ice Sheet are vulnerable to an instability that could lead to rapid ice sheet collapse, significantly raising sea levels, but the timing and rates of collapse are highly uncertain. In response to such a large‐scale loss of overlying ice, viscoelastically deforming mantle material uplifts the surface, alleviating some drivers of unstable ice sheet retreat. While previous studies have focused on the effects mantle deformation has on continental ice dynamics over centuries to millennia, recent seismic observations suggest that the mantle beneath West Antarctica is hot and weak, potentially affecting local glacial dynamics over timescales as short as decades. To measure the importance of viscoelastic uplift in stabilizing grounding line retreat, we coupled a high‐resolution ice flow model to a viscoelastically deforming mantle. We find that rapid viscoelastic uplift can reduce the total volume of ice lost over 150 years by 30%, or 18 mm of equivalent sea level rise, making it an essential process to consider when using models to project the future evolution of marine‐based ice retreat.Key PointsWe examine the feedback between ice sheet dynamics and solid Earth viscoelastic deformation on grounding line stabilityThe viscoelastic response of a low viscosity mantle stabilizes the marine ice sheet instability over decades to centuriesViscoelastic uplift on timescales similar to grounding line migration can be a leading term in the feedback ice sheets/solid EarthPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/155486/1/grl60591-sup-0001-Text_SI-S01.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155486/2/grl60591.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155486/3/grl60591_am.pd

Preliminary design characteristics of a subsonic business jet concept employing an aspect ratio 25 strut braced wing

The advantages of replacing the conventional wing on a transatlantic business jet with a larger, strut braced wing of aspect ratio 25 were evaluated. The lifting struts reduce both the induced drag and structural weight of the heavier, high aspect ratio wing. Compared to the conventional airplane, the strut braced wing design offers significantly higher lift to drag ratios achieved at higher lift coefficients and, consequently, a combination of lower speeds and higher altitudes. The strut braced wing airplane provides fuel savings with an attendant increase in construction costs

Must naive realists be relationalists?

Relationalism maintains that perceptual experience involves, as part of its nature, a distinctive kind of conscious perceptual relation between a subject of experience and an object of experience. Together with the claim that perceptual experience is presentational, relationalism is widely believed to be a core aspect of the naive realist outlook on perception. This is a mistake. I argue that naive realism about perception can be upheld without a commitment to relationalism

Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart

This is the final version. It was first published by Wiley in The Journal of Physiology at http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2014.275263/abstract.Hypoxic exposure is associated with impaired cardiac energetics in humans and altered mitochondrial function, with suppressed complex I-supported respiration, in rat heart. This response might limit reactive oxygen species (ROS) generation, but at the cost of impaired electron transport chain (ETC) activity. Dietary nitrate supplementation improves mitochondrial efficiency and can promote tissue oxygenation by enhancing blood flow. We therefore hypothesised that ETC dysfunction, impaired energetics and oxidative damage in the hearts of rats exposed to chronic hypoxia could be alleviated by sustained administration of a moderate dose of dietary nitrate. Male Wistar rats (n=40) were given water supplemented with 0.7 mmol/L NaCl (as control) or 0.7 mmol/L NaNO3, elevating plasma nitrate levels by 80%, and were exposed to 13% O2 (hypoxia) or normoxia (n=10 per group) for 14 days. Respiration rates, ETC protein levels, mitochondrial density, ATP content and protein carbonylation were measured in cardiac muscle. Complex I respiration rates and protein levels were 33% lower in hypoxic/NaCl rats compared with normoxic/NaCl controls. Protein carbonylation was 65% higher in hearts of hypoxic rats compared with controls, indicating increased oxidative stress, whilst ATP levels were 62% lower. Respiration rates, complex I protein and activity, protein carbonylation and ATP levels were all fully protected in the hearts of nitrate-supplemented hypoxic rats. Both in normoxia and hypoxia, dietary nitrate suppressed cardiac arginase expression and activity and markedly elevated cardiac L-arginine concentrations, unmasking a novel mechanism of action by which nitrate enhances tissue NO bioavailability. Dietary nitrate therefore alleviates metabolic abnormalities in the hypoxic heart, improving myocardial energetics